UCSD School of Medicine examines the effects of timed eating on metabolic health

In a joint study on timed eating, the UC San Diego School of Medicine and the Salk Institute found that limiting food consumption to a 10-hour window each day, within an hour of to wake up three hours before going to bed, to improve heart health. in patients with metabolic syndrome. TIMET clinical trials were sponsored by National Institute of Diabetes and Digestive and Kidney Diseases and was recently published in the September 30 issue of Annals of Internal Medicine.

Metabolic syndrome is a diagnosis classified by having three or more different medical conditions that can lead to heart disease and diabetes. Medical conditions include increased blood sugar, blood pressure, cholesterol, waist circumference, and triglycerides, a type of lipid found in the blood.

Michael Wilkinson, study author and assistant professor of medicine in the Department of Cardiovascular Medicine at UCSD, spoke to The Guardian.

“Our hypothesis for this study was that when people eat for a long time every day, so if you wake up in the morning and have something to eat or eat after time, you expose the body to external nutrients and calories through the body’s circadian metabolism,” Wilkinson said.

The circadian rhythm is the body’s internal clock. It regulates many biologic functions that occur during the day, including metabolism.

“When people eat in the middle of the day, their bodies are ready to process that food and make good use of it. But if you’re eating late at night, the clock your cycle tells you your metabolism ‘you have to stop now,’ but we ignore that, and we continue to eat until night.”

When a person continues to eat food throughout the day, the body’s circadian rhythm is disturbed, so the person’s metabolism cannot work properly, “especially the way the body deals with food and blood sugar.”

Satchidananda Pandaacademic corresponding author and professor at the Salk Institute, spoke with UC San Diego Today about the relationship between TRE and the body’s ability to control natural processes through circadian rhythms.

“With less time to eat, we restore the body’s natural intelligence and use its daily circadian rhythms to restore metabolism and improve health,” said Panda.

Participants in the experimental group showed significant improvement in blood sugar and cholesterol levels after completing TRE for three months. Low hemoglobin A1C test results were also seen. This test evaluates a patient’s average blood sugar over a three-month period and the likelihood of being diagnosed with type 2 diabetes or prediabetes.

The results of the tests presented below by TRE show how intermittent fasting can reduce a patient’s risk of developing metabolic diseases.

The Guardian asked about some of the potential limitations of the study including patients’ diet and exercise. In response, Wilkinson explained how a 24-hour dietary recall conducted by a dietician and the use of motion detectors were used to check for any significant changes in dietary intake. halori from the beginning and end of the study.

“We have data from wrist-worn actigraphy devices that we used at the beginning and end of the study to ensure that there was no significant change in exercise that could affect our findings,” he said. “There was no data in the materials to suggest that what we were seeing was clearly influenced by any change in operating conditions during the study period.”

The university’s efforts to evaluate the effect of TRE on metabolic health are ongoing.

“We have been fortunate to collaborate with our fellow researchers at the Salk Institute on some clinical trials during the restricted period at UCSD,” said Wilkinson.